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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIST1H1E
All Species:
34.85
Human Site:
S51
Identified Species:
76.67
UniProt:
P10412
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10412
NP_005312.1
219
21865
S51
I
T
K
A
V
A
A
S
K
E
R
S
G
V
S
Chimpanzee
Pan troglodytes
XP_001172808
221
22291
S52
I
T
K
A
V
A
A
S
K
E
R
S
G
V
S
Rhesus Macaque
Macaca mulatta
P40286
208
22075
S55
I
T
E
A
L
S
V
S
Q
E
R
V
G
M
S
Dog
Lupus familis
XP_853847
290
29282
S106
I
T
K
A
V
A
A
S
K
E
R
S
G
V
S
Cat
Felis silvestris
Mouse
Mus musculus
P43274
219
21959
S51
I
T
K
A
V
A
A
S
K
E
R
S
G
V
S
Rat
Rattus norvegicus
P15865
219
21969
S51
I
T
K
A
V
A
A
S
K
E
R
S
G
V
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515094
223
22581
S51
I
T
K
A
V
S
V
S
K
E
R
N
G
V
S
Chicken
Gallus gallus
P08284
219
22026
S52
I
T
K
A
V
S
A
S
K
E
R
K
G
L
S
Frog
Xenopus laevis
P06893
220
22422
S55
I
V
K
A
V
S
S
S
K
E
R
S
G
V
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P02255
256
26341
K61
D
A
S
I
K
N
L
K
E
R
G
G
S
S
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P19375
205
22145
F51
K
K
Y
I
A
T
N
F
D
V
Q
M
D
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.5
55.7
57.2
N.A.
94
95.4
N.A.
79.8
73.9
58.6
N.A.
N.A.
43.3
N.A.
N.A.
41.1
Protein Similarity:
100
87.3
68
62
N.A.
95.4
97.2
N.A.
87
79.4
66.3
N.A.
N.A.
52.3
N.A.
N.A.
50.6
P-Site Identity:
100
100
53.3
100
N.A.
100
100
N.A.
80
80
80
N.A.
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
93.3
93.3
93.3
N.A.
N.A.
6.6
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
82
10
46
55
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
0
0
10
0
0
0
10
0
0
% D
% Glu:
0
0
10
0
0
0
0
0
10
82
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
10
10
82
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
82
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
73
0
10
0
0
10
73
0
0
10
0
0
0
% K
% Leu:
0
0
0
0
10
0
10
0
0
0
0
0
0
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% M
% Asn:
0
0
0
0
0
10
10
0
0
0
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
10
0
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
0
0
10
82
0
0
10
0
% R
% Ser:
0
0
10
0
0
37
10
82
0
0
0
55
10
10
82
% S
% Thr:
0
73
0
0
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
73
0
19
0
0
10
0
10
0
64
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _